Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190627 | 1.00 | GAA (0.49) | GAASMN1; SMN2ALOX15HTR1DHTR1B | |
| SCHEMBL14909872 | 0.90 | GRM4 (0.43) | GAASMN1; SMN2HTR1DHTR1BGRM4 | |
| SCHEMBL31251289 | 0.90 | GRM4 (0.43) | GAASMN1; SMN2HTR1DHTR1BGRM4 | |
| SCHEMBL13135674 | 0.80 | SMN1; SMN2 (0.46) | GAASMN1; SMN2ALOX15HTR1DHTR1B | |
| SCHEMBL29190685 | 0.78 | MAPT (0.45) | GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30833689 | 0.78 | MAPT (0.45) | GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25337095 | 0.75 | GAA (0.42) | GAASMN1; SMN2ALOX15PDE7AP2RX7 | |
| SCHEMBL3358219 | 0.73 | HTR1D (0.43) | GAASMN1; SMN2ALOX15HTR1DHTR1B | |
| SCHEMBL3358945 | 0.73 | ALOX15 (0.52) | GAASMN1; SMN2ALOX15HTR1DHTR1B | |
| SCHEMBL21198529 | 0.72 | GAA (0.47) | GAAGRM4PDE7AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |