Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190685 | 1.00 | MAPT (0.45) | MAPTL3MBTL1ACHESIRT6APP | |
| SCHEMBL14910849 | 0.91 | MAPT (0.47) | MAPTL3MBTL1ACHESMN1; SMN2CNR2 | |
| SCHEMBL29190627 | 0.78 | GAA (0.49) | MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30833690 | 0.78 | GAA (0.49) | MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL3352685 | 0.78 | MAPT (0.47) | MAPTACHESIRT6APPBCHE | |
| SCHEMBL29190609 | 0.78 | MAPT (0.47) | MAPTL3MBTL1ACHESIRT6APP | |
| SCHEMBL30833686 | 0.78 | MAPT (0.47) | MAPTL3MBTL1ACHESIRT6APP | |
| SCHEMBL3355202 | 0.77 | GLS (0.50) | MAPTACHESIRT6SMN1; SMN2PKM | |
| SCHEMBL29377201 | 0.77 | GLS (0.50) | MAPTACHESIRT6SMN1; SMN2PKM | |
| SCHEMBL16308649 | 0.76 | MAPT (0.40) | MAPTL3MBTL1ACHESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |