Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190623 | 1.00 | GLS (0.59) | GLSNPC1MAPTPOLBATM | |
| SCHEMBL7803875 | 0.92 | GLS (0.56) | GLSNPC1MAPTPOLBATM | |
| SCHEMBL2933655 | 0.89 | GLS (0.75) | GLSNPC1MAPTPOLBATM | |
| SCHEMBL9551797 | 0.88 | GLS (0.55) | GLSNPC1MAPTPOLBATM | |
| SCHEMBL14923499 | 0.86 | GLS (0.59) | GLSNPC1MAPTPOLBATM | |
| SCHEMBL22126712 | 0.86 | GLS (0.59) | GLSNPC1MAPTHTR2AHTR2C | |
| SCHEMBL7804091 | 0.83 | GLS (0.60) | GLSNPC1MAPTHTR2AHTR2C | |
| SCHEMBL22502262 | 0.83 | GLS (0.56) | GLSNPC1MAPTHTR2AHTR2C | |
| SCHEMBL20770037 | 0.82 | GLS (0.55) | GLSNPC1MAPTPOLBKMO | |
| SCHEMBL2149894 | 0.82 | GLS (0.55) | GLSNPC1MAPTPOLBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |