Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502262 | 0.86 | GLS (0.56) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL7803875 | 0.86 | GLS (0.56) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL22126712 | 0.83 | GLS (0.59) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL14923499 | 0.83 | GLS (0.59) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL30833705 | 0.83 | GLS (0.59) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL29190623 | 0.83 | GLS (0.59) | GLSNPC1KMOMAPTHTR2A | |
| SCHEMBL6069456 | 0.83 | GLS (0.53) | GLSNPC1KMOMAPTCNR1 | |
| SCHEMBL3781560 | 0.83 | GLS (0.53) | GLSNPC1KMOMAPTLMNA | |
| SCHEMBL20770037 | 0.80 | GLS (0.55) | GLSNPC1KMOMAPTLMNA | |
| SCHEMBL9551797 | 0.80 | GLS (0.55) | GLSNPC1KMOMAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1510034-A | Indazole compound, preparing method thereof and medicine composition containing the same | ɪά��ʵ���� | 2004-07-07 | — | — | CN | disclosed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6046205-A | FOR TREATMENT OF VENOUS INSUFFICIENCY AND OF ASSOCIATED DISORDERS, AND ALSO IN THE TREATMENT OF MIGRAINE | ADIR ET COMPAGNIE (FR) | 2000-04-04 | — | — | US | disclosed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |