Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 4/20 | 0.50 |
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | ULK1 | O75385 | 5/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833779 | 0.84 | EGFR (0.48) | CDK1IGF1RMAPK8ULK1GSK3B | |
| SCHEMBL29190667 | 0.81 | CDK1 (0.56) | CDK1IGF1RSTK17BSTK17AMAPK8 | |
| SCHEMBL29190630 | 0.80 | EGFR (0.54) | CDK1IGF1RSTK17AMAPK8ULK1 | |
| SCHEMBL30833768 | 0.79 | ALK (0.46) | CDK1IGF1RSTK17AMAPK8CLK2 | |
| SCHEMBL21374195 | 0.79 | CDK1 (0.56) | CDK1IGF1RSTK17AMAPK8ULK1 | |
| SCHEMBL30833671 | 0.79 | JAK2 (0.42) | CDK1IGF1RSTK17AMAPK8ULK1 | |
| SCHEMBL30833634 | 0.79 | IGF1R (0.46) | IGF1RMAPK8 | |
| SCHEMBL29190628 | 0.79 | IGF1R (0.46) | IGF1RMAPK8 | |
| SCHEMBL30833790 | 0.79 | IGF1R (0.44) | CDK1IGF1RMAPK8CDK19ALK | |
| SCHEMBL30833758 | 0.78 | SYK (0.46) | IGF1RSTK17AMAPK8CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |