Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 15/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833779 | 0.85 | EGFR (0.48) | IGF1RCDK1MAPK8CDK19ALK | |
| SCHEMBL30833774 | 0.85 | IGF1R (0.43) | IGF1RNTRK1CDK1MAPK8CDK19 | |
| SCHEMBL30833669 | 0.83 | ALK (0.46) | ALK | |
| SCHEMBL29190622 | 0.82 | GLO1 (0.53) | IGF1RCDK1CDK19ALK | |
| SCHEMBL29190628 | 0.81 | IGF1R (0.46) | IGF1RNTRK1MAPK8 | |
| SCHEMBL30833634 | 0.81 | IGF1R (0.46) | IGF1RNTRK1MAPK8 | |
| SCHEMBL30833709 | 0.79 | CDK1 (0.55) | IGF1RCDK1MAPK8CDK19ALK | |
| SCHEMBL30833768 | 0.79 | ALK (0.46) | IGF1RCDK1MAPK8CDK19ALK | |
| SCHEMBL30833785 | 0.78 | ALK (0.51) | IGF1RALK | |
| SCHEMBL30833628 | 0.75 | IGF1R (0.46) | IGF1RNTRK1MAPK8CDK19ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |