Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145207 | 1.00 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL27259505 | 0.77 | ESR1 (0.40) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL25411517 | 0.77 | IDO1 (0.43) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL24104233 | 0.77 | ADORA2A (0.35) | PTGER3ADORA2AADORA2BALDH1A1KDM4E | |
| SCHEMBL29426945 | 0.77 | IDO1 (0.43) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL21608298 | 0.77 | ATAD2 (0.37) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL15910540 | 0.77 | PTGER3 (0.41) | PTGER3ADORA2AADORA2BTSHR | |
| SCHEMBL16626052 | 0.76 | POLB (0.36) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL21608335 | 0.76 | PI4KA (0.37) | PI4KAPI4K2BPI4K2API4KBPTGER3 | |
| SCHEMBL15910714 | 0.75 | TRPA1 (0.40) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |