Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190689 | 1.00 | MAPK1 (0.44) | MAPK1HRH3PDPK1JAK2PIK3CA | |
| SCHEMBL29190556 | 0.87 | MAPK1 (0.54) | MAPK1PDPK1JAK2PIK3CAAXL | |
| SCHEMBL29190522 | 0.86 | KCNH2 (0.44) | MAPK1JAK2AXLFGFR1FLT1 | |
| SCHEMBL30833743 | 0.86 | KCNH2 (0.44) | MAPK1JAK2AXLFGFR1FLT1 | |
| SCHEMBL30833680 | 0.81 | MAPK1 (0.43) | MAPK1HRH3L3MBTL1 | |
| SCHEMBL29190586 | 0.81 | MAPK1 (0.43) | MAPK1HRH3L3MBTL1 | |
| SCHEMBL30833677 | 0.81 | MAPK1 (0.43) | MAPK1HRH3L3MBTL1 | |
| SCHEMBL761105 | 0.77 | MAPK1 (0.54) | MAPK1PDPK1JAK2PIK3CAAXL | |
| SCHEMBL30833725 | 0.74 | AXL (0.50) | MAPK1JAK2AXL | |
| SCHEMBL4785556 | 0.74 | AXL (0.50) | MAPK1JAK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |