SCHEMBL30833677 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK1	P28482	2/20	0.43

▸	ALDH1A1	P00352	4/20	0.41

▸	MEN1	O00255	3/20	0.39

▸	KMT2A	Q03164	3/20	0.39

▸	CYP1A2	P05177	1/20	0.39

▸	CYP2C9	P11712	1/20	0.39

▸	HPGD	P15428	1/20	0.39

▸	POLB	P06746	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	RHOA	P61586	1/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.38

▸	MAPT	P10636	1/20	0.38

▸	ACHE	P22303	1/20	0.37

▸	HRH3	Q9Y5N1	1/20	0.37

▸	AKR1C3	P42330	1/20	0.37

▸	SMN1; SMN2	Q16637	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30833680	1.00	MAPK1 (0.43)	MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL29190586	1.00	MAPK1 (0.43)	MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL29190669	0.89	MAPK1 (0.52)	MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL30833685	0.89	MAPK1 (0.52)	MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL30833752	0.87	MEN1 (0.41)	MAPK1ALDH1A1MEN1KMT2ARHOA
SCHEMBL29190644	0.87	MEN1 (0.41)	MAPK1ALDH1A1MEN1KMT2ARHOA
SCHEMBL30833762	0.81	MAPK1 (0.44)	MAPK1L3MBTL1HRH3
SCHEMBL29190689	0.81	MAPK1 (0.44)	MAPK1L3MBTL1HRH3
SCHEMBL2466571	0.79	MAPK1 (0.52)	MAPK1ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL4784574	0.77	SIRT6 (0.50)	MAPK1ALDH1A1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-113896744-B	Selective EGFR inhibitor	成都先导药物开发股份有限公司	2024-04-16	—	—	CN	disclosed