Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.53 |
| ▸ | CDK9 | P50750 | 7/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.53 |
| ▸ | CCNK | O75909 | 6/20 | 0.53 |
| ▸ | CCND3 | P30281 | 6/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190576 | 1.00 | CDK2 (0.53) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL29190618 | 0.81 | ALK (0.59) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL21558104 | 0.80 | BCL6 (0.58) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL29014829 | 0.78 | LRRK2 (0.53) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL30483190 | 0.78 | LRRK2 (0.53) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL29761996 | 0.77 | CCNA2 (0.43) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL30833778 | 0.77 | CCNA2 (0.43) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL15600758 | 0.77 | CCNA2 (0.43) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL29190653 | 0.77 | LRRK2 (0.48) | CDK2CDK9CCNA2CCNKCCND3 | |
| SCHEMBL30833650 | 0.77 | LRRK2 (0.48) | CDK2CDK9CCNA2CCNKCCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |