Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CCNK | O75909 | 4/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.46 |
| ▸ | CCND3 | P30281 | 3/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833650 | 1.00 | LRRK2 (0.48) | LRRK2JAK2CCNA2CDK2CCNK | |
| SCHEMBL29190558 | 0.84 | ULK1 (0.45) | LRRK2JAK2CCNA2CDK2CCNK | |
| SCHEMBL30948622 | 0.81 | EGFR (0.59) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29806050 | 0.80 | CCNA2 (0.59) | LRRK2JAK2CCNA2CDK2CCNK | |
| SCHEMBL30429763 | 0.79 | CDK2 (0.47) | JAK2CCNA2CDK2CCNKCDK9 | |
| SCHEMBL30833798 | 0.79 | ULK1 (0.58) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29190692 | 0.79 | ULK1 (0.58) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29806018 | 0.78 | KDR (0.46) | CCNA2CDK2CCNKCDK9MAPK9 | |
| SCHEMBL30948600 | 0.77 | EGFR (0.49) | CCNA2CDK2CCNKCDK9MAPK9 | |
| SCHEMBL31059280 | 0.77 | CCNA2 (0.47) | LRRK2CCNA2CDK2CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |