Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 4/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190579 | 0.91 | ELANE (0.41) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL3516872 | 0.91 | ELANE (0.43) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL1709876 | 0.83 | ELANE (0.47) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL3514299 | 0.83 | ELANE (0.46) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL1316854 | 0.82 | PDGFRA (0.42) | ELANEMAP2K4GABRG2GABRB3GABRA5 | |
| SCHEMBL30833750 | 0.82 | MAP2K4 (0.39) | BRD4MAP2K4GABRG2GABRB3GABRA5 | |
| SCHEMBL6170318 | 0.82 | MAPT (0.44) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL22777374 | 0.82 | MAPT (0.44) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL3964153 | 0.82 | MAPT (0.44) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL15081365 | 0.82 | ELANE (0.43) | ELANEF2PLAUCTRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |