Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709876 | 0.87 | ELANE (0.47) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL22777374 | 0.86 | MAPT (0.44) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL3964153 | 0.86 | MAPT (0.44) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL27585778 | 0.84 | ELANE (0.42) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL2922296 | 0.83 | ELANE (0.41) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL6375106 | 0.82 | L3MBTL1 (0.52) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL30833809 | 0.82 | ELANE (0.41) | MAPTALDH1A1LMNAELANEF2 | |
| SCHEMBL12090381 | 0.81 | MAP2K4 (0.38) | LMNABRD4MEN1KMT2AGABRG2 | |
| SCHEMBL2304349 | 0.81 | ESR2 (0.43) | MEN1KMT2AGABRG2GABRB3GABRA5 | |
| SCHEMBL12999396 | 0.81 | ELANE (0.40) | MAPTALDH1A1LMNAELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20030078431-A1 | Antithrombotic agents | BEIGHT DOUGLAS WADE (US) | 2003-04-24 | — | — | US | disclosed |
| US-6500851-B2 | ANTICOAGULANT IN MAMMLS | ELI LILLY AND COMPANY | 2002-12-31 | — | — | US | disclosed |
| US-20020173518-A1 | Antithrombotic agents | BEIGHT DOUGLAS WADE (US) | 2002-11-21 | — | — | US | disclosed |
| US-6372759-B1 | BLOOD COAGULATION FACTOR XA FOR MAMMALS | ELI LILLY AND COMPANY | 2002-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173518-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | MAPT 4730/4885ALDH1A1 323/4885LMNA 1410/4885 |
| US-20030078431-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | MAPT 4730/4885ALDH1A1 323/4885LMNA 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.