Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 13/20 | 0.83 |
| ▸ | IL1B | P01584 | 9/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296688 | 0.91 | NLRP3 (0.69) | NLRP3IL1B | |
| SCHEMBL25257733 | 0.91 | NLRP3 (0.69) | NLRP3IL1B | |
| SCHEMBL30488592 | 0.91 | NLRP3 (0.69) | NLRP3IL1B | |
| SCHEMBL25213293 | 0.91 | NLRP3 (1.00) | NLRP3IL1BKCNH2 | |
| SCHEMBL25300120 | 0.90 | NLRP3 (0.73) | NLRP3IL1BKCNH2 | |
| SCHEMBL25255374 | 0.90 | NLRP3 (0.73) | NLRP3IL1BKCNH2 | |
| SCHEMBL25302205 | 0.89 | NLRP3 (0.67) | NLRP3IL1BKCNH2 | |
| SCHEMBL25302208 | 0.89 | NLRP3 (0.67) | NLRP3IL1BKCNH2 | |
| SCHEMBL30833866 | 0.89 | NLRP3 (0.67) | NLRP3IL1BKCNH2 | |
| SCHEMBL25301833 | 0.88 | IL1B (0.74) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |