Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 7/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834020 | 1.00 | IL1B (0.44) | IL1BNLRP3HDAC4HDAC6TRPV1 | |
| SCHEMBL30893678 | 0.91 | NLRP3 (0.45) | IL1BNLRP3USP30AHCYPIM1 | |
| SCHEMBL30834021 | 0.91 | NLRP3 (0.45) | IL1BNLRP3USP30AHCYPIM1 | |
| SCHEMBL29030471 | 0.90 | USP30 (0.37) | NLRP3USP30AHCYPIM1PIM2 | |
| SCHEMBL29030472 | 0.90 | USP30 (0.37) | NLRP3USP30AHCYPIM1PIM2 | |
| SCHEMBL30488526 | 0.90 | USP30 (0.37) | NLRP3USP30AHCYPIM1PIM2 | |
| SCHEMBL30488591 | 0.90 | USP30 (0.37) | NLRP3USP30AHCYPIM1PIM2 | |
| SCHEMBL30833963 | 0.89 | IL1B (0.44) | IL1BNLRP3HDAC4HDAC6TRPV1 | |
| SCHEMBL30833954 | 0.89 | IL1B (0.44) | IL1BNLRP3HDAC4HDAC6TRPV1 | |
| SCHEMBL31681915 | 0.85 | IL1B (0.48) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |