Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | IL1B | P01584 | 7/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833942 | 1.00 | NLRP3 (0.48) | NLRP3KCNH2IL1BTNFCHRM1 | |
| SCHEMBL30833972 | 0.88 | NLRP3 (0.48) | NLRP3KCNH2IL1BTNFCHRM1 | |
| SCHEMBL30833934 | 0.83 | NLRP3 (0.38) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30833899 | 0.83 | NLRP3 (0.38) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30834033 | 0.80 | IL1B (0.46) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL25857850 | 0.78 | NLRP3 (0.42) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL29030538 | 0.78 | IL1B (0.72) | NLRP3IL1B | |
| Hydrochloric Acid SCHEMBL31681894 | 0.78 | NLRP3 (0.51) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL25856166 | 0.78 | IL1B (0.72) | NLRP3IL1B | |
| SCHEMBL31127458 | 0.74 | NLRP3 (0.46) | NLRP3KCNH2IL1BTNFCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |