Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 10/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488542 | 0.88 | IL1B (0.52) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL25256063 | 0.88 | IL1B (0.52) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL30833880 | 0.88 | IL1B (0.40) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL31681907 | 0.86 | IL1B (0.56) | IL1BTNFNLRP3 | |
| SCHEMBL30834030 | 0.83 | IL1B (0.48) | IL1BTNFNLRP3 | |
| SCHEMBL31681915 | 0.81 | IL1B (0.48) | IL1BTNFNLRP3 | |
| SCHEMBL30488552 | 0.81 | IL1B (0.35) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL25302371 | 0.81 | IL1B (0.35) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL30834037 | 0.80 | NLRP3 (0.38) | IL1BTNFNLRP3ALDH1A1 | |
| SCHEMBL25258660 | 0.80 | NLRP3 (0.37) | IL1BTNFNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |