SCHEMBL30833973

SCHEMBL30833973

C#Cc1ccc(-c2nnc(N[C@@H]3CCCN(C)C3)cc2C(F)(F)F)c(O)c1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IL1B P01584 14/20 0.77
NLRP3 Q96P20 10/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30833951 0.88 IL1B (0.59) IL1BNLRP3
SCHEMBL31681934 0.88 IL1B (0.59) IL1BNLRP3
SCHEMBL22655033 0.87 IL1B (1.00) IL1BNLRP3
SCHEMBL22654843 0.87 IL1B (1.00) IL1BNLRP3
SCHEMBL31329531 0.87 IL1B (1.00) IL1BNLRP3
SCHEMBL25301834 0.87 IL1B (0.74) IL1BNLRP3
SCHEMBL25301833 0.87 IL1B (0.74) IL1BNLRP3
SCHEMBL22654930 0.87 IL1B (1.00) IL1BNLRP3
SCHEMBL22654871 0.87 IL1B (1.00) IL1BNLRP3
SCHEMBL22654845 0.87 IL1B (1.00) IL1BNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4613749-A1 NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF TransThera Sciences (Nanjing), Inc. (CN) 2025-09-10 EP disclosed
CN-117986258-A NLRP3 inflammation corpuscle inhibitor and application thereof 药捷安康(南京)科技股份有限公司 2024-05-07 CN disclosed