Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681934 | 1.00 | IL1B (0.59) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL30833973 | 0.88 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL25296688 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL25257733 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL30488592 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL30833996 | 0.86 | NLRP3 (0.54) | IL1BNLRP3 | |
| SCHEMBL31681897 | 0.86 | IL1B (0.48) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL25214158 | 0.82 | NLRP3 (0.78) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL25299892 | 0.79 | NLRP3 (0.49) | IL1BNLRP3 | |
| SCHEMBL25299893 | 0.79 | NLRP3 (0.49) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |