Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833874 | 1.00 | IL1B (0.45) | IL1BTNFKCNH2NLRP3KDM4E | |
| SCHEMBL26943723 | 1.00 | IL1B (0.45) | IL1BTNFKCNH2NLRP3KDM4E | |
| SCHEMBL26943683 | 0.78 | TYRO3 (0.38) | IL1BTNF | |
| SCHEMBL26437406 | 0.77 | IL1B (0.43) | IL1BTNFKCNH2NLRP3SYK | |
| SCHEMBL30375383 | 0.77 | IL1B (0.43) | IL1BTNFKCNH2NLRP3SYK | |
| SCHEMBL26092068 | 0.77 | IL1B (0.43) | IL1BTNFKCNH2NLRP3SYK | |
| SCHEMBL30834044 | 0.75 | SYK (0.47) | KCNH2NLRP3KDM4EMEN1NPC1 | |
| SCHEMBL26437415 | 0.73 | IL1B (0.43) | IL1BTNFKCNH2NLRP3SYK | |
| SCHEMBL26089652 | 0.73 | IL1B (0.43) | IL1BTNFKCNH2NLRP3SYK | |
| SCHEMBL26091725 | 0.72 | IL1B (0.49) | IL1BTNFKCNH2NLRP3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |