Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833874 | 0.75 | IL1B (0.45) | SYKHTR1AKDM4EMEN1NPC1 | |
| SCHEMBL26943723 | 0.75 | IL1B (0.45) | SYKHTR1AKDM4EMEN1NPC1 | |
| SCHEMBL30833991 | 0.75 | IL1B (0.45) | SYKHTR1AKDM4EMEN1NPC1 | |
| SCHEMBL22068319 | 0.69 | SYK (0.64) | SYKKCNH2ZAP70 | |
| SCHEMBL23030353 | 0.68 | SMN1; SMN2 (0.54) | KDM4EALDH1A1LMNAHTTMEN1 | |
| SCHEMBL20194474 | 0.68 | SMN1; SMN2 (0.49) | SYKKDM4EALDH1A1LMNAHTT | |
| SCHEMBL18415611 | 0.68 | SMN1; SMN2 (0.49) | SYKKDM4EALDH1A1LMNAHTT | |
| SCHEMBL7793274 | 0.68 | SMN1; SMN2 (0.49) | SYKKDM4EALDH1A1LMNAHTT | |
| SCHEMBL23004981 | 0.68 | SMN1; SMN2 (0.54) | KDM4EALDH1A1LMNAHTTMEN1 | |
| SCHEMBL23004986 | 0.67 | HTR1A (0.51) | SYKHTR1AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094185-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | 药捷安康(南京)科技股份有限公司 | 2024-05-10 | — | — | WO | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |