Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488562 | 0.83 | MAPT (0.35) | NLRP3 | |
| SCHEMBL30488542 | 0.82 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL25256063 | 0.82 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL30833979 | 0.76 | IL1B (0.36) | IL1BTNFNLRP3 | |
| SCHEMBL25861524 | 0.76 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL25301017 | 0.76 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL30834030 | 0.76 | IL1B (0.48) | IL1BTNFNLRP3 | |
| SCHEMBL30833872 | 0.75 | IL1B (0.53) | IL1BTNFNLRP3 | |
| SCHEMBL30833880 | 0.73 | IL1B (0.40) | IL1BTNFNLRP3 | |
| SCHEMBL30833941 | 0.73 | IL1B (0.55) | IL1BTNFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |