Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.36 |
| ▸ | IL1B | P01584 | 5/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834033 | 0.84 | IL1B (0.46) | NLRP3IL1BTNFPGRNR3C2 | |
| SCHEMBL30833934 | 0.83 | NLRP3 (0.38) | NLRP3IL1BTNF | |
| SCHEMBL30833899 | 0.83 | NLRP3 (0.38) | NLRP3IL1BTNF | |
| SCHEMBL30834000 | 0.79 | NLRP3 (0.42) | NLRP3IL1B | |
| SCHEMBL25857924 | 0.79 | CACNA2D1 (0.32) | NLRP3 | |
| SCHEMBL25299192 | 0.78 | IL1B (0.54) | NLRP3IL1B | |
| Iodide SCHEMBL31681896 | 0.78 | NLRP3 (0.40) | NLRP3IL1BTNF | |
| SCHEMBL25299193 | 0.78 | IL1B (0.54) | NLRP3IL1B | |
| SCHEMBL30833872 | 0.77 | IL1B (0.53) | NLRP3IL1BTNF | |
| SCHEMBL25302439 | 0.77 | NLRP3 (0.54) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |