Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | LDLR | P01130 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834345 | 0.77 | LDLR (0.41) | PDPK1HPGDSIDO1PDE10ALDLR | |
| SCHEMBL30834347 | 0.75 | PDPK1 (0.43) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| SCHEMBL3138241 | 0.69 | SIRT6 (0.56) | SIRT6 | |
| SCHEMBL25136318 | 0.68 | PDPK1 (0.39) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| Hydrochloric Acid SCHEMBL29182228 | 0.67 | PDPK1 (0.38) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| SCHEMBL25136493 | 0.66 | GSK3B (0.38) | PDPK1GSK3BDYRK1AWNT1TTK | |
| SCHEMBL30182657 | 0.66 | GSK3B (0.38) | PDPK1GSK3BDYRK1AWNT1TTK | |
| SCHEMBL30595615 | 0.66 | BRD9 (0.48) | HPGDSIDO1PDE10AHTR1AHTR7 | |
| SCHEMBL24921970 | 0.66 | MAPT (0.50) | CYP11B1LRRK2 | |
| SCHEMBL16785552 | 0.64 | IDO1 (0.43) | PDPK1HPGDSIDO1LDLRPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |