Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834345 | 0.79 | LDLR (0.41) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| SCHEMBL30834339 | 0.75 | PDPK1 (0.41) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| SCHEMBL4022684 | 0.73 | HPGDS (0.54) | HPGDSIDO1LDLRPCSK9HTR6 | |
| SCHEMBL25136408 | 0.68 | PDPK1 (0.39) | PDPK1HPGDSIDO1CYP3A4 | |
| SCHEMBL16018259 | 0.68 | ALOX5AP (0.38) | ALOX5APPIK3R1PIK3CAMTORPIK3CD | |
| Hydrochloric Acid SCHEMBL29182167 | 0.67 | PDPK1 (0.39) | PDPK1HPGDSIDO1CYP3A4 | |
| SCHEMBL23900740 | 0.67 | CDK8 (0.39) | PDPK1 | |
| SCHEMBL16785552 | 0.67 | IDO1 (0.43) | PDPK1HPGDSIDO1LDLRPCSK9 | |
| SCHEMBL8428522 | 0.67 | HPGDS (0.43) | HPGDSIDO1LDLRPCSK9HTR6 | |
| SCHEMBL30363640 | 0.67 | IDO1 (0.44) | PDPK1HPGDSIDO1LDLRPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |