Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.57 |
| ▸ | CDK9 | P50750 | 2/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | CCND1 | P24385 | 3/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.53 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PRKACG | P22612 | 2/20 | 0.53 |
| ▸ | PRKACB | P22694 | 2/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834685 | 0.86 | CCNT1 (0.74) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL30834701 | 0.86 | CAMK2D (0.74) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL8464191 | 0.82 | CCNT1 (0.52) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL8464380 | 0.82 | PRKD1 (0.61) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL18392213 | 0.81 | CAMK2D (0.53) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL8477009 | 0.81 | CCNT1 (0.51) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL30834693 | 0.80 | CCNE2 (0.74) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL8074697 | 0.78 | PRKD1 (0.58) | CCNT1CDK9PIM1CAMK2DCCNE2 | |
| SCHEMBL28374335 | 0.77 | GSK3B (0.48) | PRKCAGSK3BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL28554172 | 0.77 | IDH1 (0.45) | PIM1CAMK2DCDK4CCND1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886799-A | Protein degradation targeting chimeric compound for targeting degradation of GSK-3 beta and application thereof | 浙江工业大学 | 2024-04-16 | — | — | CN | disclosed |