Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531651 | 1.00 | LPL (0.37) | LPLLIPGEGFRANPEPLAP3 | |
| SCHEMBL17531645 | 0.89 | EGFR (0.34) | LPLLIPGEGFR | |
| SCHEMBL30728959 | 0.84 | NCF1 (0.42) | LPLLIPGKDM4E | |
| SCHEMBL476912 | 0.84 | NCF1 (0.42) | LPLLIPGKDM4E | |
| SCHEMBL481508 | 0.79 | MAPT (0.42) | LPLLIPGEGFRKDM4E | |
| SCHEMBL29982045 | 0.79 | MAPT (0.42) | LPLLIPGEGFRKDM4E | |
| SCHEMBL2027186 | 0.75 | LPL (0.48) | LPLLIPGANPEPLAP3 | |
| SCHEMBL17531612 | 0.75 | KDM4E (0.33) | KDM4EGPR3 | |
| SCHEMBL16112454 | 0.72 | CYP1A2 (0.50) | LPLLIPGKDM4E | |
| SCHEMBL31651605 | 0.72 | CYP1A2 (0.50) | LPLLIPGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059212-A2 | 6,6 WESTERN CORE COMPOUNDS AS MGLU5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | VANDERBILT UNIVERSITY (US) | 2024-03-21 | — | — | WO | disclosed |