SCHEMBL30835892

SCHEMBL30835892

CC(C)(C)OC(=O)N1CC(CC=Cc2cc(C(F)(F)F)on2)C1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 1/20 0.37
▸ NR1H2 P55055 1/20 0.37
▸ HDAC4 P56524 4/20 0.36
▸ HDAC6 Q9UBN7 3/20 0.35
▸ IDO1 P14902 1/20 0.35
▸ GPR119 Q8TDV5 5/20 0.35
▸ STS P08842 1/20 0.35
▸ TACR1 P25103 2/20 0.35
▸ AKT1 P31749 1/20 0.35
▸ PIK3CA P42336 1/20 0.35
▸ MTOR P42345 1/20 0.35
▸ RORC P51449 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27401990 0.84 HDAC4 (0.38) NR1H2HDAC4HDAC6GPR119STS
SCHEMBL31556570 0.84 HDAC4 (0.38) NR1H2HDAC4HDAC6GPR119STS
SCHEMBL27399251 0.82 TEAD1 (0.36) —
SCHEMBL27399252 0.82 TEAD1 (0.36) —
SCHEMBL31556521 0.78 NR1H2 (0.40) NAMPTNR1H2HDAC4HDAC6IDO1
SCHEMBL30835897 0.77 HDAC4 (0.37) NR1H2HDAC4HDAC6GPR119STS
SCHEMBL27401664 0.77 HDAC4 (0.37) NR1H2HDAC4HDAC6GPR119STS
SCHEMBL30835908 0.77 USP30 (0.38) NR1H2HDAC4HDAC6GPR119STS
SCHEMBL30835987 0.76 SCD5 (0.38) HDAC4HDAC6GPR119STSRORC
SCHEMBL30835823 0.74 SCD5 (0.40) HDAC4HDAC6GPR119STSHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587424-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS Bridgene Biosciences, Inc. (US) 2025-07-23 — — EP disclosed
CN-119894866-A YAP/TAZ-TEAD oncoprotein inhibitors 布里奇恩生物科学公司 2025-04-25 — — CN disclosed
WO-2024059317-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS BRIDGENE BIOSCIENCES, INC. (US) 2024-03-21 — — WO disclosed
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