SCHEMBL30835897

SCHEMBL30835897

CC1(C=Cc2cc(C(F)(F)F)on2)CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HDAC4 P56524 4/20 0.37
▸ USP30 Q70CQ3 2/20 0.36
▸ SCD5 Q86SK9 2/20 0.36
▸ NR1H2 P55055 1/20 0.35
▸ STS P08842 1/20 0.34
▸ HDAC1 Q13547 1/20 0.33
▸ GPR119 Q8TDV5 4/20 0.33
▸ HDAC6 Q9UBN7 3/20 0.33
▸ RORC P51449 1/20 0.33
▸ MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27401664 1.00 HDAC4 (0.37) HDAC4USP30SCD5NR1H2STS
SCHEMBL30835908 0.89 USP30 (0.38) HDAC4USP30SCD5NR1H2STS
SCHEMBL30835995 0.85 HDAC4 (0.35) HDAC4USP30SCD5STSGPR119
SCHEMBL27399138 0.82 CNR1 (0.32) —
SCHEMBL30835916 0.82 CNR1 (0.32) —
SCHEMBL30835987 0.81 SCD5 (0.38) HDAC4USP30SCD5STSGPR119
SCHEMBL30835823 0.80 SCD5 (0.40) HDAC4USP30SCD5STSHDAC1
SCHEMBL31556570 0.79 HDAC4 (0.38) HDAC4USP30NR1H2STSHDAC1
SCHEMBL27401990 0.79 HDAC4 (0.38) HDAC4USP30NR1H2STSHDAC1
SCHEMBL27401178 0.79 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587424-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS Bridgene Biosciences, Inc. (US) 2025-07-23 — — EP disclosed
CN-119894866-A YAP/TAZ-TEAD oncoprotein inhibitors 布里奇恩生物科学公司 2025-04-25 — — CN disclosed
WO-2024059317-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS BRIDGENE BIOSCIENCES, INC. (US) 2024-03-21 — — WO disclosed
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