Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 6/20 | 0.33 |
| ▸ | JAK2 | O60674 | 5/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835897 | 0.85 | HDAC4 (0.37) | HDAC4USP30SCD5GPR119STS | |
| SCHEMBL30835908 | 0.85 | USP30 (0.38) | HDAC4USP30SCD5GPR119STS | |
| SCHEMBL27401664 | 0.85 | HDAC4 (0.37) | HDAC4USP30SCD5GPR119STS | |
| SCHEMBL30835929 | 0.82 | CNR1 (0.31) | — | |
| SCHEMBL27399663 | 0.82 | CNR1 (0.31) | — | |
| SCHEMBL30835987 | 0.78 | SCD5 (0.38) | HDAC4USP30SCD5GPR119STS | |
| SCHEMBL30835823 | 0.77 | SCD5 (0.40) | HDAC4USP30SCD5GPR119F2R | |
| SCHEMBL31556570 | 0.76 | HDAC4 (0.38) | HDAC4USP30GPR119MTORSTS | |
| SCHEMBL30835842 | 0.76 | MAPT (0.43) | JAK1JAK2GPR119 | |
| SCHEMBL27401990 | 0.76 | HDAC4 (0.38) | HDAC4USP30GPR119MTORSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |