SCHEMBL3083596

SCHEMBL3083596

CC(C)(C)NC(=O)c1cccc(NC(=O)C(C)(C)C)c1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.71
LMNA P02545 4/20 0.64
KMT2A Q03164 3/20 0.60
ANO1 Q5XXA6 9/20 0.57
ALDH1A1 P00352 1/20 0.57
GAA P10253 1/20 0.56
MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21198297 0.86 LMNA (0.66) LMNAKMT2AANO1GAAMEN1
SCHEMBL5502669 0.86 LMNA (0.66) LMNAKMT2AANO1GAAMEN1
SCHEMBL3798155 0.83 NPSR1 (0.81) NPSR1KMT2AALDH1A1MEN1
SCHEMBL1948517 0.83 MEN1 (0.56) NPSR1LMNAKMT2AANO1ALDH1A1
SCHEMBL11364641 0.83 MEN1 (0.53) NPSR1LMNAKMT2AANO1ALDH1A1
SCHEMBL22633595 0.83 KMT2A (0.67) LMNAKMT2AANO1GAAMEN1
SCHEMBL18232992 0.82 LMNA (0.65) LMNAKMT2AANO1GAAMEN1
SCHEMBL12852616 0.82 LMNA (0.61) LMNAKMT2AANO1GAAMEN1
SCHEMBL7824768 0.82 NPSR1 (0.78) NPSR1LMNAKMT2AALDH1A1MEN1
SCHEMBL21249304 0.81 LMNA (0.58) LMNAKMT2AANO1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed