Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.80 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.75 |
| ▸ | PDE8A | O60658 | 3/20 | 0.75 |
| ▸ | C5AR1 | P21730 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99985 | 1.00 | PDE7A (0.80) | PDE7APDE7BPDE8AC5AR1MEN1 | |
| SCHEMBL30837831 | 0.90 | PDE7A (0.83) | PDE7APDE7BPDE8AMEN1TP53 | |
| SCHEMBL100713 | 0.90 | PDE7A (0.83) | PDE7APDE7BPDE8AMEN1TP53 | |
| SCHEMBL99998 | 0.90 | PDE7A (0.88) | PDE7APDE7BPDE8AMEN1TP53 | |
| SCHEMBL7878461 | 0.90 | PDE7A (0.82) | PDE7APDE7BPDE8AC5AR1MEN1 | |
| SCHEMBL30837886 | 0.89 | PDE7A (1.00) | PDE7APDE7BPDE8AC5AR1MEN1 | |
| SCHEMBL100608 | 0.89 | PDE7A (1.00) | PDE7APDE7BPDE8AC5AR1MEN1 | |
| SCHEMBL100114 | 0.88 | PDE7A (0.80) | PDE7APDE7BPDE8AMEN1TP53 | |
| SCHEMBL30837972 | 0.88 | PDE7A (1.00) | PDE7APDE7BPDE8AC5AR1MEN1 | |
| SCHEMBL100698 | 0.88 | PDE7A (1.00) | PDE7APDE7BPDE8AC5AR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |