Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 3/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30838019 | 0.81 | HTR3A (0.42) | CYP11B1CYP11B2 | |
| Formic Acid SCHEMBL30837982 | 0.81 | HTR3A (0.42) | CYP11B1CYP11B2 | |
| Formic Acid SCHEMBL30838033 | 0.79 | PKM (0.43) | IL1BCYP11B1CYP11B2MAPK1 | |
| Formic Acid SCHEMBL30838101 | 0.78 | CHEK1 (0.36) | IL1BCYP11B1CYP11B2MAPK1 | |
| Formic Acid SCHEMBL30838087 | 0.77 | HRH4 (0.41) | CYP11B1CYP11B2 | |
| Formic Acid SCHEMBL30838066 | 0.76 | HRH4 (0.44) | CYP11B1CYP11B2 | |
| Formic Acid SCHEMBL30838032 | 0.76 | PTK2 (0.40) | CYP11B1CYP11B2 | |
| Formic Acid SCHEMBL30838073 | 0.76 | PRKCQ (0.41) | IL1BCYP11B1CYP11B2 | |
| SCHEMBL30838084 | 0.74 | CYP11B1 (0.41) | CYP11B1CYP11B2CCNKCDK7CDK9 | |
| SCHEMBL27095187 | 0.74 | CHEK1 (0.38) | CYP11B1CYP11B2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059677-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | CEREVANCE LTD (GB) | 2024-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059677-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | CHRNA6, CHRM2, CHRNA1 | IL1B 3527/4885MC4R 2225/4885MAPK3 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.