Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30838580 | 1.00 | FAAH (0.69) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL30838577 | 1.00 | FAAH (0.69) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL9526860 | 1.00 | FAAH (0.69) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL15623807 | 1.00 | FAAH (0.69) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL9526869 | 1.00 | FAAH (0.69) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL15602675 | 0.98 | FAAH (0.66) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL9550539 | 0.98 | FAAH (0.66) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL15680128 | 0.94 | FAAH (0.63) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL14331545 | 0.94 | FAAH (0.63) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL12295267 | 0.94 | FAAH (0.63) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024012565-A1 | MEMANTINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2024-01-18 | — | — | WO | disclosed |