Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10122766 | 1.00 | KDM4E (0.49) | KDM4EMAPTDRD4DRD2CA12 | |
| SCHEMBL1091532 | 0.94 | MAPT (0.54) | KDM4EMAPTDRD4DRD2CA12 | |
| SCHEMBL154428 | 0.86 | DRD4 (0.64) | KDM4EMAPTDRD4DRD2HTR2A | |
| SCHEMBL25058873 | 0.85 | HTR2A (0.46) | KDM4EMAPTCA12CA1CA2 | |
| Bromide SCHEMBL949153 | 0.84 | DRD4 (0.62) | KDM4EMAPTDRD4DRD2HTR2A | |
| SCHEMBL6247150 | 0.81 | DRD2 (0.75) | KDM4EMAPTDRD4DRD2CA12 | |
| Bromide SCHEMBL3182004 | 0.79 | DRD2 (0.72) | KDM4EMAPTDRD4DRD2CA12 | |
| SCHEMBL3873031 | 0.78 | HTR2A (0.47) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL30853463 | 0.78 | HTR2A (0.47) | KDM4EMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL2334738 | 0.77 | HTR2A (0.46) | KDM4EMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119310215-B | Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection | 珠海前列药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119310215-A | Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection | 珠海前列药业有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119310215-B | Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection | 珠海前列药业有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119310215-A | Method for detecting impurity content in tolvaptan sodium phosphate freeze-dried powder injection | 珠海前列药业有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-117756717-A | Tolvaptan intermediate and preparation method of tollvaptan | 广州市桐晖药业有限公司 | 2024-03-26 | — | — | CN | disclosed |