Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882979 | 0.90 | NR1H4 (0.41) | NR1H4EPHX2HTR2CCHRM2CHRM3 | |
| SCHEMBL31534627 | 0.83 | KDM4E (0.38) | NR1H4EPHX2HTR2CCHRM2CHRM3 | |
| SCHEMBL30839694 | 0.83 | KDM4E (0.38) | NR1H4EPHX2HTR2CCHRM2CHRM3 | |
| SCHEMBL30839697 | 0.82 | KMT2A (0.42) | NR1H4KAT6AKAT5 | |
| SCHEMBL4015052 | 0.81 | PDK2 (0.43) | HTR2CCHRM2CHRM3MAOACHRNA4 | |
| SCHEMBL8169606 | 0.76 | SLC6A4 (0.42) | NR1H4EPHX2HTR2CCHRM2CHRM3 | |
| SCHEMBL23882988 | 0.73 | ALDH1A1 (0.38) | NR1H4KAT6AKAT5 | |
| SCHEMBL16993182 | 0.72 | L3MBTL1 (0.62) | HTR2CPDK2L3MBTL1SLC6A4 | |
| SCHEMBL991922 | 0.72 | PDK2 (0.53) | PDK2KAT6AKAT5KDM4E | |
| SCHEMBL31305087 | 0.72 | CHRM2 (0.41) | NR1H4EPHX2HTR2CCHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067792-A1 | FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |