Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355957 | 0.88 | HSD17B10 (0.45) | ALDH1A1NR1H4HSD17B10KMT2APDK1 | |
| SCHEMBL12013087 | 0.86 | ALDH1A1 (0.47) | ALDH1A1NR1H4MAPTNPC1RAB9A | |
| SCHEMBL18147257 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL18157850 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30369746 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2APDK1PDK2PDK3 | |
| SCHEMBL5671504 | 0.83 | L3MBTL1 (0.49) | ALDH1A1NR1H4KMT2AMAPTNPC1 | |
| SCHEMBL15156110 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL27270132 | 0.82 | ALDH1A1 (0.42) | ALDH1A1NR1H4HSD17B10KMT2AMAPT | |
| SCHEMBL19442220 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7270578 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2APDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948028-A | Condensed-cyclic compound, pharmaceutical composition and application thereof | 海南先声再明医药股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024067792-A1 | FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |