SCHEMBL30839724

SCHEMBL30839724

Nc1cc(Cl)cc(-c2ccc(N)c(Cl)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.65
TSHR P16473 6/20 0.65
ALDH1A1 P00352 6/20 0.65
MAPK1 P28482 1/20 0.65
ESR2 Q92731 1/20 0.55
TP53 P04637 3/20 0.46
ALOX15 P16050 3/20 0.41
THRB P10828 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27186011 1.00 CYP3A4 (0.65) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL29365311 0.82 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL49382 0.82 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL8872306 0.82 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL23137319 0.80 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL864592 0.80 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL30242948 0.80 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL29368557 0.80 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL2571374 0.80 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Methane SCHEMBL27949876 0.80 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO claimed
CN-120092033-A Novel polyurethane or polyurethane-urea compositions with enhanced low temperature properties 英格维蒂英国有限公司 2025-06-03 CN claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP disclosed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO disclosed
CN-120092033-A Novel polyurethane or polyurethane-urea compositions with enhanced low temperature properties 英格维蒂英国有限公司 2025-06-03 CN disclosed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO disclosed