SCHEMBL30839733

SCHEMBL30839733

Nc1ccc(Cl)cc1-c1cccc(Cl)c1N

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
CYP3A4 P08684 2/20 0.48
RECQL P46063 1/20 0.46
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALOX15 P16050 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TP53 P04637 1/20 0.43
IDO1 P14902 4/20 0.41
FADS1 O60427 1/20 0.38
HTR2B P41595 1/20 0.38
PDE4D Q08499 1/20 0.38
S100A4 P26447 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GFER P55789 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27185998 1.00 TSHR (0.48) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
SCHEMBL2502453 0.85 TSHR (0.48) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
SCHEMBL30839728 0.81 TSHR (0.65) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
SCHEMBL30839807 0.81 TSHR (0.46) TSHRALDH1A1SMN1; SMN2KDM4E
SCHEMBL16347053 0.81 TSHR (0.46) TSHRALDH1A1SMN1; SMN2KDM4E
SCHEMBL11517368 0.81 TSHR (0.65) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
SCHEMBL20345882 0.79 ALDH1A1 (0.59) TSHRCYP3A4ALDH1A1SMN1; SMN2ALOX15
SCHEMBL9732124 0.77 TSHR (0.58) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL29274500 0.76 TSHR (0.71) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2
SCHEMBL22517291 0.74 CYP3A4 (0.45) TSHRCYP3A4RECQLALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP disclosed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO disclosed