Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537242 | 0.79 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL6602326 | 0.78 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL6012107 | 0.72 | AKR1B1 (0.36) | TSHR | |
| SCHEMBL21981517 | 0.72 | CES1 (0.39) | TSHRCTSK | |
| SCHEMBL9848119 | 0.71 | TDP1 (0.35) | TSHR | |
| SCHEMBL787672 | 0.70 | CES2 (0.41) | TSHR | |
| SCHEMBL28326775 | 0.69 | CES2 (0.43) | TSHR | |
| SCHEMBL12948689 | 0.69 | CES2 (0.43) | TSHR | |
| SCHEMBL28360214 | 0.69 | CES2 (0.43) | TSHR | |
| SCHEMBL28126297 | 0.69 | CES2 (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583972-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Sionna Therapeutics Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |