Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840683 | 0.89 | TYR (0.56) | HSD17B1HSP90AB1HSD17B3HTTMAPT | |
| SCHEMBL10454859 | 0.87 | PTPN1 (0.47) | HSD17B1PRKCIPTPN1PTPN11HSP90AB1 | |
| SCHEMBL10658033 | 0.87 | CES2 (0.50) | HSD17B1PRKCIPTPN1PTPN11HSP90AB1 | |
| SCHEMBL8271835 | 0.86 | HSD17B1 (0.73) | HSD17B1HSP90AB1HTTMAPTCA12 | |
| Acetic Acid SCHEMBL6129825 | 0.86 | PTPN1 (0.51) | HSD17B1PRKCIPTPN1PTPN11HSP90AB1 | |
| SCHEMBL9745 | 0.85 | PTPN1 (0.54) | PTPN1PTPN11HSP90AB1HSD17B3HTT | |
| SCHEMBL16863862 | 0.85 | PRKCI (0.50) | HSD17B1PRKCIPTPN1PTPN11HSP90AB1 | |
| SCHEMBL28295794 | 0.84 | PTPN1 (0.53) | PTPN1PTPN11HSP90AB1HSD17B3HTT | |
| Potassium Ion SCHEMBL851715 | 0.82 | HSD17B3 (0.45) | HSD17B1PRKCIPTPN1PTPN11HSP90AB1 | |
| SCHEMBL137806 | 0.82 | HSD17B3 (0.45) | HSD17B1PTPN1PTPN11HSP90AB1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795166-B2 | Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method | N.E. CHEMCAT CORPORATION (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070155617-A1 | FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD | N. E. CHEMCAT CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |
| US-5767310-A | Phenoxyphenylacetic acid derivatives | MERCK & CO., INC. (US) | 1998-06-16 | — | — | US | disclosed |
| US-5668176-A | ENDOTHELIN ANTAGONIST | MERCK & CO. INC. (US) | 1997-09-16 | — | — | US | disclosed |
| US-5565485-A | TREATING CARDIOVASCULAR DISORDERS | MERCK & CO., INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1996009818-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS FOR THE TREATMENT OF EMESIS | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |
| CN-1119434-A | Phenoxyphenylacetic acid derivatives | MERCK & CO INC (US) | 1996-03-27 | — | — | CN | disclosed |
| WO-1996004905-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-02-22 | — | — | WO | disclosed |
| WO-1994021590-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0617001-A1 | Phenoxyphenylacetic acid derivatives | MERCK & CO. INC. (US) | 1994-09-28 | — | — | EP | disclosed |