Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.63 |
| ▸ | LAP3 | P28838 | 2/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076457 | 0.91 | FDPS (0.60) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL3088085 | 0.81 | — | — | |
| SCHEMBL3087933 | 0.80 | FDPS (0.40) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL16798849 | 0.77 | FDPS (0.68) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL8334357 | 0.77 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL9701607 | 0.77 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL3815170 | 0.77 | FDPS (0.68) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL9614565 | 0.77 | FDPS (1.00) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL16799205 | 0.77 | FDPS (0.68) | FDPSLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL6442013 | 0.77 | FDPS (0.68) | FDPSLAP3S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| US-7776844-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2010-08-17 | — | — | US | disclosed |
| US-20090208499-A1 | N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use | YU RUEY J | 2009-08-20 | — | — | US | disclosed |
| US-7572776-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2009-08-11 | — | — | US | disclosed |
| US-20080306025-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2008-12-11 | — | — | US | disclosed |
| US-7429575-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2008-09-30 | — | — | US | disclosed |
| US-20070161543-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2007-07-12 | — | — | US | disclosed |