Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30840137 | 0.90 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL27287191 | 0.77 | RHEB (0.30) | — | |
| SCHEMBL30840330 | 0.77 | RHEB (0.30) | — | |
| SCHEMBL27285201 | 0.75 | PRKCI (0.38) | TRPA1METKDRFLT3BTK | |
| SCHEMBL31625824 | 0.73 | MET (0.33) | TRPA1MET | |
| SCHEMBL31625866 | 0.70 | RHEB (0.30) | — | |
| SCHEMBL27287176 | 0.70 | RHEB (0.30) | — | |
| SCHEMBL31625951 | 0.69 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL27285206 | 0.69 | ASH1L (0.36) | TRPA1 | |
| SCHEMBL30840375 | 0.69 | TTBK1 (0.33) | METLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583972-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Sionna Therapeutics Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |