Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546219 | 0.82 | TP53 (0.41) | KMT2AMEN1HDAC6TP53ALDH1A1 | |
| SCHEMBL30842135 | 0.79 | POLB (0.46) | KMT2AMEN1HDAC6TP53ALDH1A1 | |
| SCHEMBL11636317 | 0.75 | MEN1 (0.52) | KMT2AMEN1HDAC6TP53ALDH1A1 | |
| SCHEMBL31546239 | 0.73 | KIF18A (0.46) | TP53 | |
| SCHEMBL11197675 | 0.73 | MEN1 (0.50) | KMT2AMEN1HDAC6ALDH1A1KDM4E | |
| SCHEMBL31546229 | 0.73 | MEN1 (0.50) | KMT2AMEN1HDAC6ALDH1A1KDM4E | |
| SCHEMBL14800043 | 0.71 | TP53 (0.57) | KMT2AMEN1TP53ALDH1A1KDM4E | |
| SCHEMBL3999493 | 0.71 | BCHE (0.45) | KMT2AMEN1HDAC6TP53ALDH1A1 | |
| SCHEMBL5511965 | 0.67 | MEN1 (0.97) | KMT2AMEN1HDAC6ALDH1A1KDM4E | |
| SCHEMBL29618881 | 0.67 | MEN1 (0.97) | KMT2AMEN1HDAC6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051755-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-03-14 | — | — | WO | disclosed |