SCHEMBL30842195

SCHEMBL30842195

CSCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.65
▸ IL23R Q5VWK5 2/20 0.59
▸ GLP1R P43220 3/20 0.59
▸ GCGR P47871 1/20 0.59
▸ GIPR P48546 1/20 0.59
▸ KEAP1 Q14145 1/20 0.58
▸ PTH1R Q03431 2/20 0.57
▸ VIPR1 P32241 2/20 0.56
▸ OPRM1 P35372 1/20 0.55
▸ OPRD1 P41143 1/20 0.55
▸ OPRK1 P41145 1/20 0.55
▸ VIPR2 P41587 2/20 0.55
▸ CCKBR P32239 1/20 0.55
▸ ECE1 P42892 1/20 0.54
▸ MUS81 Q96NY9 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31211751 0.93 TFPI (0.61) TFPIIL23RGLP1RGCGRGIPR
Acetic Acid SCHEMBL29533494 0.91 TFPI (0.69) TFPIKEAP1PTH1RVIPR1OPRM1
SCHEMBL29387068 0.91 TFPI (0.69) TFPIKEAP1PTH1RVIPR1OPRM1
SCHEMBL29366672 0.91 TFPI (0.69) TFPIKEAP1PTH1RVIPR1OPRM1
SCHEMBL29405667 0.91 TFPI (0.66) TFPIKEAP1OPRM1OPRD1OPRK1
SCHEMBL30842196 0.90 OPRM1 (0.64) TFPIOPRM1OPRD1OPRK1
SCHEMBL30863947 0.90 TFPI (0.66) TFPIOPRM1OPRD1OPRK1
SCHEMBL30524359 0.89 TFPI (0.61) TFPIIL23RGLP1RGCGRGIPR
Tyrlysseraspserphetyrglyleumet SCHEMBL30475005 0.89 OPRM1 (0.61) TFPIIL23ROPRM1OPRD1OPRK1
SCHEMBL30277897 0.89 TFPI (0.60) TFPIIL23RGLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US claimed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US claimed
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US disclosed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US disclosed
US-11911464-B2 Anti-parasitic immunological compositions PROMMUNE, INC. (US) 2024-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides C5AR1, C5AR2, C3AR1 TFPI 1772/4885IL23R 1055/4885GLP1R 635/4885
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS C3AR1, C5AR1, C5AR2 TFPI 895/4885IL23R 538/4885GLP1R 1960/4885
US-11911464-B2 Anti-parasitic immunological compositions C3AR1, C5AR1, C5AR2 TFPI 895/4885IL23R 538/4885GLP1R 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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