SCHEMBL29366672

SCHEMBL29366672

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CSSC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.69
▸ KEAP1 Q14145 1/20 0.55
▸ KISS1R Q969F8 4/20 0.55
▸ VIPR1 P32241 2/20 0.55
▸ NMUR2 Q9GZQ4 2/20 0.55
▸ NMUR1 Q9HB89 2/20 0.55
▸ PTH1R Q03431 1/20 0.54
▸ VIPR2 P41587 1/20 0.54
▸ OPRM1 P35372 1/20 0.53
▸ OPRD1 P41143 1/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ NPY4R P50391 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387068 1.00 TFPI (0.69) TFPIKEAP1KISS1RVIPR1NMUR2
Acetic Acid SCHEMBL29533494 0.99 TFPI (0.69) TFPIKEAP1KISS1RVIPR1NMUR2
SCHEMBL29405667 0.92 TFPI (0.66) TFPIKEAP1OPRM1OPRD1OPRK1
SCHEMBL30863947 0.92 TFPI (0.66) TFPIOPRM1OPRD1OPRK1NPY4R
SCHEMBL30842195 0.91 TFPI (0.65) TFPIKEAP1VIPR1PTH1RVIPR2
SCHEMBL30436216 0.90 TFPI (0.79) TFPIVIPR1VIPR2
SCHEMBL29548324 0.90 TFPI (0.63) TFPIKISS1RNPY4R
SCHEMBL30601869 0.89 TFPI (0.79) TFPIVIPR1VIPR2
SCHEMBL30842196 0.89 OPRM1 (0.64) TFPIKISS1ROPRM1OPRD1OPRK1
SCHEMBL29368760 0.89 TFPI (0.61) TFPIKISS1RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 — — WO claimed
US-20240327520-A1 METHODS AND COMPOSITIONS FOR PKC-DELTA INHIBITION AND CANCER IMMUNOTHERAPY THE UNIVERSITY OF CHICAGO (US) 2024-10-03 — — US claimed
WO-2023081934-A1 METHODS AND COMPOSITIONS FOR PKC-DELTA INHIBITION AND CANCER IMMUNOTHERAPY THE UNIVERSITY OF CHICAGO (US) 2023-05-11 — — WO claimed
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles CLEARSIDE BIOMEDICAL, INC. (US) 2026-05-28 — — US disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
US-20250345206-A1 APPARATUS AND METHODS FOR OCULAR INJECTION CLEARSIDE BIOMEDICAL, INC. (US) 2025-11-13 — — US disclosed
US-20250304916-A1 METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS TRAILHEAD BIOSYSTEMS INC (US) 2025-10-02 — — US disclosed
EP-3891158-B1 MAP4K4 INHIBITORS IMPERIAL COLLEGE INNOVATIONS LTD (GB) 2025-09-10 — — EP disclosed
US-12350261-B2 Methods and devices for the treatment of ocular diseases in human subjects CLEARSIDE BIOMEDICAL, INC. (US) 2025-07-08 — — US disclosed
US-20250186253-A1 DEVICES AND METHODS FOR ADJUSTING THE INSERTION DEPTH OF A NEEDLE FOR MEDICAMENT DELIVERY CLEARSIDE BIOMEDICAL, INC. (US) 2025-06-12 — — US disclosed
EP-4566672-A2 METHODS FOR THE TREATMENT OF OCULAR DISEASE IN HUMAN SUBJECTS Clearside Biomedical Inc. (US) 2025-06-11 — — EP disclosed
US-11559428-B2 Apparatus and methods for ocular injection CLEARSIDE BIOMEDICAL, INC. (US) 2023-01-24 — — US disclosed
EP-2887982-B1 APPARATUS FOR DRUG DELIVERY USING MICRONEEDLES CLEARSIDE BIOMEDICAL INC (US) 2022-11-23 — — EP disclosed
US-11504431-B2 Formulations for the suprachoroidal space of an eye and methods EMORY UNIVERSITY (US) 2022-11-22 — — US disclosed
WO-2022221720-A1 ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF NOVARTIS AG (CH) 2022-10-20 — — WO disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 — — US disclosed
US-20220280341-A1 APPARATUS AND METHODS FOR DRUG DELIVERY USING MICRONEEDLES CLEARSIDE ROYALTY LLC 2022-09-08 — — US disclosed
US-20220280386-A1 METHODS AND APPARATUS FOR EXTRACTING FLUID FROM CONTAINER CLEARSIDE BIOMEDICAL, INC. 2022-09-08 — — US disclosed
WO-2022076938-A1 APPARATUS AND METHODS OF RETINAL INJECTION CLEARSIDE BIOMEDICAL, INC. (US) 2022-04-14 — — WO disclosed
CN-110177527-B Device and method for adjusting insertion depth of needle for medicament delivery 科尼尔赛德生物医学公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327520-A1 METHODS AND COMPOSITIONS FOR PKC-DELTA INHIBITION AND CANCER IMMUNOTHERAPY PRKCB, PRKCG, PRKCA TFPI 2329/4885KEAP1 2424/4885KISS1R 4815/4885
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles PROKR2, SLC10A2, GLP1R TFPI 986/4885KEAP1 4720/4885KISS1R 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback