Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20741453 | 1.00 | TLR7 (0.55) | TLR7TLR8NLRP3NUDT1 | |
| SCHEMBL20475956 | 0.92 | TLR7 (0.62) | TLR7TLR8NLRP3 | |
| SCHEMBL26863056 | 0.89 | NLRP3 (0.56) | TLR7TLR8NLRP3 | |
| SCHEMBL20476287 | 0.87 | TLR7 (0.39) | TLR7TLR8NLRP3 | |
| SCHEMBL30842214 | 0.87 | TLR7 (0.39) | TLR7TLR8NLRP3 | |
| SCHEMBL22814334 | 0.86 | TLR7 (0.55) | TLR7TLR8NLRP3 | |
| SCHEMBL30842225 | 0.86 | NLRP3 (0.74) | TLR7TLR8NLRP3 | |
| SCHEMBL20475941 | 0.86 | NLRP3 (0.74) | TLR7TLR8NLRP3 | |
| SCHEMBL30842212 | 0.86 | NLRP3 (0.59) | TLR7TLR8NLRP3 | |
| SCHEMBL20741464 | 0.86 | NLRP3 (0.59) | TLR7TLR8NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325534-B | Substituted imidazoquinolines as NLRP3 modulators | 先天肿瘤免疫公司 | 2024-04-05 | — | — | CN | disclosed |