SCHEMBL30843232

SCHEMBL30843232

Oc1cccc(Oc2ccccn2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.50
TLR2 O60603 1/20 0.50
MGLL Q99685 1/20 0.50
GRM5 P41594 1/20 0.48
FFAR4 Q5NUL3 1/20 0.47
MAP4K4 O95819 1/20 0.45
KDM4E B2RXH2 1/20 0.44
RET P07949 1/20 0.43
KIF5B P33176 1/20 0.43
KDR P35968 1/20 0.43
IP6K1 Q92551 1/20 0.43
IP6K3 Q96PC2 1/20 0.43
IP6K2 Q9UHH9 1/20 0.43
PPARG P37231 1/20 0.42
RAB9A P51151 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
CYP3A4 P08684 1/20 0.41
PTGS2 P35354 2/20 0.40
MBD2 Q9UBB5 1/20 0.40
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582155 1.00 TLR4 (0.50) TLR4TLR2MGLLGRM5FFAR4
SCHEMBL29612417 0.87 TLR4 (0.56) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL12129555 0.87 TLR4 (0.56) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL15602369 0.85 TLR4 (0.55) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL5686998 0.83 SCN7A (0.47) TLR4TLR2MGLLKDM4EPPARG
SCHEMBL15387423 0.82 HRH3 (0.44) TLR4TLR2MGLLGRM5FFAR4
SCHEMBL3334396 0.82 ESR2 (0.53) TLR4TLR2MGLLGRM5MAP4K4
SCHEMBL5109000 0.81 MAP4K4 (0.57) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL12168388 0.81 F2 (0.53) KDM4ERETKIF5BKDRRAB9A
SCHEMBL6091732 0.81 CHRNB2 (0.51) MGLLAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110272456-B Organometallic compound and organic light emitting device including the same 三星显示有限公司 2024-04-05 CN disclosed