Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458231 | 1.00 | ALOX5AP (0.36) | ALOX5APFEN1P2RX7FGFR1FGFR4 | |
| SCHEMBL30843253 | 0.84 | FGFR1 (0.36) | ALOX5APFEN1P2RX7FGFR1FGFR4 | |
| SCHEMBL21458240 | 0.84 | FGFR1 (0.36) | ALOX5APFEN1P2RX7FGFR1FGFR4 | |
| SCHEMBL21458308 | 0.83 | P2RX7 (0.39) | P2RX7FGFR1FGFR4KMT2ASMN1; SMN2 | |
| SCHEMBL30843257 | 0.83 | P2RX7 (0.39) | P2RX7FGFR1FGFR4KMT2ASMN1; SMN2 | |
| SCHEMBL21506727 | 0.82 | CNR2 (0.38) | JAK2 | |
| SCHEMBL21506728 | 0.82 | CNR2 (0.44) | OPRL1 | |
| SCHEMBL21458267 | 0.80 | PTGER4 (0.41) | KMT2AOPRL1MDM2 | |
| SCHEMBL21481863 | 0.80 | PTGER4 (0.41) | KMT2AOPRL1MDM2 | |
| SCHEMBL21458317 | 0.77 | NPBWR1 (0.39) | KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313208-B | Bicyclic carboxamides and methods of use thereof | 泰普斯特医疗公司 | 2024-04-19 | — | — | CN | disclosed |