SCHEMBL3084336

SCHEMBL3084336

Cc1ccc(S(=O)(=O)OC(C(=O)c2ccccc2)C(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.46
ALDH1A1 P00352 6/20 0.43
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
LMNA P02545 4/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3089316 0.93 STAT3 (0.41) ALDH1A1TDP1CES2CES1LMNA
SCHEMBL3096091 0.87 RECQL (0.49) RECQLALDH1A1TDP1TP53NPSR1
SCHEMBL10807674 0.85 RECQL (0.50) RECQLALDH1A1TDP1TP53NPSR1
SCHEMBL10811604 0.80 MMP9 (0.40) ALDH1A1LMNACA12CA1CA2
SCHEMBL60545 0.80 CYP3A4 (0.51) RECQLALDH1A1TDP1TP53NPSR1
SCHEMBL8695489 0.79 KCNA5 (0.38) RECQLALDH1A1NPSR1LMNAMAPT
SCHEMBL3089042 0.79 KMT2A (0.49) ALDH1A1TDP1CES2CES1LMNA
SCHEMBL2773393 0.78 SLC1A3 (0.44) RECQLALDH1A1TDP1LMNACA12
SCHEMBL28080723 0.78 SLC1A3 (0.44) RECQLALDH1A1TDP1LMNACA12
SCHEMBL28419808 0.78 KMT2A (0.43) ALDH1A1LMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP claimed
EP-0084515-B1 ACID-CURABLE COMPOSITION CONTAINING A BLOCKED CATALYST, AND A CURING METHOD CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
US-4510290-A LATENCY; LOW-TEMPERATURE CURING BY SHORTWAVE RADIATION; INKS, LACQUERS CIBA GEIGY CORPORATION (US) 1985-04-09 US claimed
US-20160137756-A1 Water Based Concentrated Product Forms of Photoinitiators Made by a Heterophase Polymerization Technique BASF SE (DE) 2016-05-19 US disclosed
EP-2035496-B1 WATER BASED CONCENTRATED PRODUCT FORMS OF PHOTOINITIATORS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE BASF SE (DE) 2014-07-30 EP disclosed
US-20100234484-A1 Water based concentrated product forms of photoinitiators made by a heterophase polymerization technique IGM GROUP B.V. (NL) 2010-09-16 US disclosed
EP-2035496-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF PHOTOINITIATORS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE Ciba Holding Inc. (CH) 2009-03-18 EP disclosed
WO-2008003601-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF PHOTOINITIATORS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP disclosed
EP-0249365-A2 Photocatalysts for vinyl compounds activated by an electron donating hetero atom LOCTITE (IRELAND) Ltd. (IE) 1987-12-16 EP disclosed
US-4708926-A SULFONIC ESTERS OF A-HYDROXYCARBONYL COMPOUNDS CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4636575-A Masked curing catalyst for acid-curable compositions CIBA-GEIGY CORPORATION (US) 1987-01-13 US disclosed
US-4510290-A LATENCY; LOW-TEMPERATURE CURING BY SHORTWAVE RADIATION; INKS, LACQUERS CIBA GEIGY CORPORATION (US) 1985-04-09 US disclosed
EP-0084515-A2 Acid-curable composition containing a blocked catalyst, and a curing method CIBA-GEIGY AG (CH) 1983-07-27 EP disclosed